Team

  • Leaders: C Poitou (PU-PH) and J Aron-Wisnewsky (MCU-PH)
  • Team Contributors: K Clément, P Tounian, B Dubern, F Marchelli
  • Main collaborators: M Tauber (F), S Farooqi (UK), A Rudich (Israel), P Kuhnen (G)

Main Objectives

Two main axes

  1. Develop innovative diagnosis and predictive factors/tools 
    1. for patient stratification
    2. to predict poor responders’ outcomes after interventions (diet or bariatric surgery) or after treatment in genetic obesities
    3. to improve and accelerate the identification of undiagnosed patients in rare obesities
    4. discover new mutation/genes/pathways in rare obesities
  2. Develop novel approaches for therapy with personalized medicine
    1. improve the comprehensive and multidisciplinary care in rare obesities from childhood to adulthood (guidelines)
    2. improve the outcomes of poor responder’s response by adding other specific interventions (physical activity, specific diet, pre or prebiotic that modulates gut microbiota)
    3. implement new treatments in rare obesities

Results

Topic 5 : outcomes predictors - Translating our fundamental research for the benefit of patients
Topic 5 : outcomes predictors - Translating our fundamental research for the benefit of patients
Progression of obesity and related complications: role of gut microbiota?
TOPIC 1
Intestine as a key player in metabolic disorders
TOPIC 2
Adipose tissue Remodeling
TOPIC 3
Systems’ biology and data integration (transversal WP)
TOPIC 4
Translating our fundamental research for the benefit of patients
TOPIC 5