Diabetes 2014 Jun;63(6):1966-77
Proinflammatory cytokines are critically involved in the alteration of adipose tissue biology leading to deterioration of glucose homeostasis in ob...
J. Pathol. 2014 Jun;233(2):183-95
Fibrosis is a hallmark of human white adipose tissue (WAT) during obesity-induced chronic inflammation. The functional impact of increased intersti...
J. Clin. Endocrinol. Metab. 2014 Mar;99(3):898-907
CONTEXT: Liver and white adipose tissue (WAT) develop inflammation and fibrosis.OBJECTIVE: The aim of the ...
Mol. Immunol. 2014 Jul;60(1):54-61
Polyreactive antibodies represent a significant fraction of immune repertoires and play an important role in the immune defense and immune homeosta...
PLoS ONE 2014;9(3):e91375
MicroRNAs are emerging as new mediators in the regulation of adipose tissue biology and the development of obesity. An important role of microRNA-1...
Chest 2014 Mar;145(3):525-533
BACKGROUND: Nocturnal hypoxia, the hallmark of OSA, is a potential contributing factor for nonalcoholic fatty liver disease (NAFLD...
Diabetes 2014 Feb;63(2):535-49
During obesity, chronic inflammation of human white adipose tissue (WAT) is associated with metabolic and vascular alterations. Endothelial cells f...
Am. J. Clin. Nutr. 2013 Dec;98(6):1385-94
BACKGROUND: The ability to identify obese subjects who will lose weight in response to energy restriction is an important strategy...
Diabetes Care 2013 Nov;36(11):3793-802
OBJECTIVE: Obesity is associated with cardiovascular risk and a low-grade inflammatory state in both blood and adipose tissue (AT)...
Int J Obes (Lond) 2013 Sep;37(9):1198-203
CONTEXT: The care of patients with hypothalamic obesity is challenging.OBJECTIVE: To compare body composit...
Nature 2013 Aug;500(7464):585-8
Complex gene-environment interactions are considered important in the development of obesity. The composition of the gut microbiota can determine t...
Nature 2013 Aug;500(7464):541-6
We are facing a global metabolic health crisis provoked by an obesity epidemic. Here we report the human gut microbial composition in a population ...
Stud Health Technol Inform 2013;192:1178
Non-alcoholic fatty liver disease (NAFLD) is a hepatic disease associated with metabolic syndrome. NAFLD covers a spectrum of liver disease from st...
Diabetologia 2013 Aug;56(8):1792-801
AIMS/HYPOTHESIS: Alterations in white adipose tissue (WAT) function, including changes in protein (adipokine) secretion and extrac...
Am. J. Clin. Nutr. 2013 Jul;98(1):16-24
BACKGROUND: Roux-en-Y gastric bypass (RYGB) surgery is one of the most efficient procedures for treating morbid obesity and result...
PLoS ONE 2013;8(6):e66788
OBJECTIVE: Evidence points to a founder of the multifunctional CCN family, NOV/CCN3, as a circulating molecule involved in cardiac...
Haemophilia 2013 May;19(3):399-402
The administration of therapeutic factor VIII (FVIII) to patients with haemophilia A induces the development of inhibitory anti-FVIII IgG in a subs...
Arterioscler. Thromb. Vasc. Biol. 2013 Apr;33(4):822-8
OBJECTIVE: We investigated the impact of several genetic variants located in genes encoding for proteins involved in biogenesis, m...
Endocrinology 2013 Mar;154(3):1069-79
The hypertrophied white adipose tissue (WAT) during human obesity produces inflammatory mediators, including cytokines (IL-6 and TNFα) and chemoki...
Atherosclerosis 2013 Mar;227(1):165-71
OBJECTIVES: To identify key determinants of plasma endogenous CETP activity and threshold value of plasma CETP activity associated...